Chondroitin is a carbohydrate compound and is present in cartilage. It gives the cartilage elasticity. Articular surface of joints are protected by cartilage (articular cartilage) and this cartilage is a tough smooth gristle that reduces friction and protects the underlying bone from wear. Damage and wear of the cartilage is seen on an x-ray as loss of joint space. Cartilage contains both glucosamine and chondroitin.

The rationale for the use of chondroitin and glucosamine as treatment of arthritis is that these two drugs, according to some, will improve the health of affected articular cartilage. Both chondroitin and glucosamine are manufactured by the body.

Chondroitin is considered a dietary supplement and as such the manufacture is not regulated. The quality of products available will vary.

It is available as chondriotin sulphate, obtained from cows’ cartilage. Make sure you purchase a recognised brand from a reputable company and check the label for ingredients. If you are not sure, ask, or consult your doctor. Do not discontinue your on going medication.

According to studies, patients with mild to moderate osteoarthritis had relief on par with NSAIDs such as ibuprofen. Trials, however, are inconclusive and a large placebo controlled trial will one day throw light on whether this drug should be an acceptable arthritis treatment.

There are no serious side effects. Reported side effects are increased intestinal gas and loose stools. It should not be given to children or taken by women considering pregnancy or who are pregnant. It may potentiate the effects of anti-coagulants.

If you are taking this drug or considering taking it in future, make your assessment on its effeciacy after three month. If you feel it is doing you some good, continue.

Dr. Phil Hariram,

Arthritis Guide.